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Updated: Feb 25, 2026

Screening for Thermotoga maritima Membrane-Bound Pyrophosphatase Inhibitors
Published on: November 23, 2019
Selective detection of pyrophosphate anion by a simple Cd(II) based terpyridine complex
Aditya Kumar Purohit1, Biswa Nath Ghosh1, Pravin Kumar Kar1
1Department of Chemistry, Veer Surendra Sai University of Technology, Burla, Sambalpur 768018, Odisha, India.
Abstract:
A simple ratiometric terpyridine-Cd(ll) complex was synthesized by the treatment of CdCl2 with terpyridine ligand 4'-(4-N,N'-dimethylaminophenyl)-2,2':6',2″-terpyridine. The synthesized complex was found to act as a selective fluorescent chemosensor for pyrophosphate P2O74- (PPi) over other anions like F-, Cl-, Br-, CO32-, SO32-, AcO-, NO2-, and H2PO4-. Furthermore, the receptor probe was also successfully employed in HeLa cell for PPi detection, which indicates this can be used as a chemosensor for cells.
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