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Updated: Feb 25, 2026
07:35
Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
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Neonatal renal cystic diseases.
Anshika Khare1, Vinod Krishnappa2, Deepak Kumar3
1a Department of Internal Medicine , Northeast Ohio Medical University , Rootstown , OH , USA.
Summary
Neonatal renal cystic diseases significantly impact infant health. Early diagnosis and intervention are crucial for better outcomes in conditions like polycystic kidney disease.
Area of Science:
- Pediatric Nephrology
- Medical Genetics
- Diagnostic Imaging
Background:
- Neonatal renal cystic diseases pose significant risks to infant morbidity and mortality.
- Understanding these conditions is vital for effective management.
Purpose of the Study:
- To provide insight into the pathophysiology, diagnosis, and treatment of neonatal renal cystic diseases.
- To emphasize the importance of early diagnosis and intervention.
Main Methods:
- A comprehensive literature search was conducted using PubMed.
- Relevant articles and reviews on neonatal renal cystic diseases were selected.
Main Results:
- Both hereditary and nonhereditary causes lead to severe outcomes.
- Ultrasound is the primary diagnostic tool, with many cases detected prenatally.
- Common conditions include autosomal dominant polycystic kidney disease, autosomal recessive polycystic kidney disease, and multicystic dysplastic kidney.
Conclusions:
- Knowledge of renal cystic diseases aids prognosis.
- Physicians must recognize the impact of early diagnosis and intervention.
- Ongoing research seeks breakthrough therapies.
Keywords:
Autosomal dominant polycystic kidney diseaseautosomal recessive polycystic kidney diseasemulticystic dysplastic kidneyneonatal renal cystic diseasesMore Related Videos
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