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Published on: June 23, 2015
Neonatal renal cystic diseases
Anshika Khare1, Vinod Krishnappa2, Deepak Kumar3
1a Department of Internal Medicine , Northeast Ohio Medical University , Rootstown , OH , USA.
Insights
Neonatal renal cystic diseases significantly impact infant health. Early diagnosis and intervention are crucial for better outcomes in conditions like polycystic kidney disease.
Area of Science:
- Pediatric Nephrology
- Medical Genetics
- Diagnostic Imaging
Background:
- Neonatal renal cystic diseases pose significant risks to infant morbidity and mortality.
- Understanding these conditions is vital for effective management.
Purpose of the Study:
- To provide insight into the pathophysiology, diagnosis, and treatment of neonatal renal cystic diseases.
- To emphasize the importance of early diagnosis and intervention.
Main Methods:
- A comprehensive literature search was conducted using PubMed.
- Relevant articles and reviews on neonatal renal cystic diseases were selected.
Main Results:
- Both hereditary and nonhereditary causes lead to severe outcomes.
- Ultrasound is the primary diagnostic tool, with many cases detected prenatally.
- Common conditions include autosomal dominant polycystic kidney disease, autosomal recessive polycystic kidney disease, and multicystic dysplastic kidney.
Conclusions:
- Knowledge of renal cystic diseases aids prognosis.
- Physicians must recognize the impact of early diagnosis and intervention.
- Ongoing research seeks breakthrough therapies.
Purpose:
Neonatal renal cystic diseases have a great impact on the morbidity and mortality of the affected neonates and infants. A good insight into the pathophysiology, diagnosis and treatment options of various neonatal renal cystic diseases aid in early diagnosis and intervention, thereby preventing complications.
Methods:
PubMed search was done for articles on "neonatal renal cystic diseases" and relevant publications including reviews were considered for our article.
Results:
Both hereditary and nonhereditary causes of cystic kidney diseases can result in severe morbidity and mortality. The main diagnostic modality is ultrasound imaging and most of the neonatal renal cystic diseases are detected during prenatal ultrasound screening. Commonly encountered neonatal renal cystic diseases are autosomal dominant polycystic kidney disease, autosomal recessive polycystic kidney disease and multicystic dysplastic kidney.
Conclusions:
A thorough knowledge of various renal cystic diseases can be of extreme prognostic value. Physicians should be aware of the impact of early diagnosis and intervention on the lives of those affected. Further research about treatment of these diseases is ongoing and can result in breakthrough therapies for these patients.
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