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Related Concept Videos

Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

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Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
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SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
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Oral Hypoglycemic Agents: Glinides01:06

Oral Hypoglycemic Agents: Glinides

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Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively...
756
Glucose Transporters01:27

Glucose Transporters

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Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
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Glucose Homeostasis: Regulation of Blood Glucose01:02

Glucose Homeostasis: Regulation of Blood Glucose

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Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
4.7K
Glucose Absorption Into the Small Intestine01:26

Glucose Absorption Into the Small Intestine

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Complex carbohydrates consumed cannot be absorbed into the small intestine in their original form. First, they must be hydrolyzed to a monosaccharide form such as glucose or galactose. These monosaccharides are then transported across the intestinal membrane and into the blood via transcellular transport. The intestinal epithelial cells allow the movement of these monosaccharides with a defined 'entry' through membrane transporter proteins present on their apical membrane and...
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Related Experiment Video

Updated: Feb 25, 2026

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
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Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

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Using Dextrose (Glucose) Gel to Reverse Neonatal Hypoglycemia.

Patricia Scheans, Catherine Bennett, Deborah Harris

    Neonatal Network : NN
    |August 3, 2017
    PubMed
    Summary

    Glucose gel effectively treats neonatal hypoglycemia (NH), reducing NICU admissions by 73% and increasing breastfeeding rates. This nurse-driven protocol improves infant health outcomes and family satisfaction while cutting costs.

    Area of Science:

    • Neonatal Medicine
    • Pediatrics
    • Nursing Practice

    Background:

    • Hospitals face pressure to enhance patient outcomes, reduce healthcare costs, and improve patient satisfaction.
    • Neonatal hypoglycemia (NH) presents a significant challenge in newborn care, often requiring intensive interventions.
    • Existing treatments for NH can be costly and may disrupt early parent-infant bonding.

    Purpose of the Study:

    • To evaluate the effectiveness of a nurse-driven protocol using glucose gel for treating neonatal hypoglycemia (NH).
    • To assess the impact of this protocol on NICU admission rates, breastfeeding success, and family cohesion.
    • To determine if this practice change aligns with hospital goals of improving outcomes, reducing costs, and increasing satisfaction.

    Main Methods:

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    Improving IV Insulin Administration in a Community Hospital
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    Measuring Uptake of the Glucose Analog, 6-(N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino)-6-Deoxyglucose, in Intact Murine Neural Retina
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    Measuring Uptake of the Glucose Analog, 6-(N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino)-6-Deoxyglucose, in Intact Murine Neural Retina

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  • Implementation of a nurse-driven protocol for neonatal hypoglycemia (NH) management.
  • Utilizing glucose gel as a standardized treatment based on randomized clinical trial findings.
  • Multidisciplinary team approach involving nurses and other healthcare professionals.

    • Main Results:

    • A 73% decrease in NICU admission rates for neonatal hypoglycemia (NH) within the first year.
    • An increase in exclusive breastfeeding rates to 49% for the studied infant population.
    • 40 additional families were able to remain together on the mother-baby unit, enhancing bonding.

    Conclusions:

    • Nurse-driven glucose gel protocols are effective in managing neonatal hypoglycemia (NH).
    • This intervention significantly improves health outcomes, reduces costly interventions, and increases patient satisfaction.
    • The protocol supports family-centered care by minimizing separation and promoting breastfeeding.