Categorizing biomedical research: the basics of translation

Area of Science:

• Biomedical Sciences
• Research Policy

Background:

• The categorization of biomedical research has not kept pace with scientific evolution.
• Current terms like 'basic research' and 'translational research' present significant conceptual issues.

Purpose of the Study:

• To review the origins and current use of 'basic' and 'translational' research terminology.
• To analyze conceptual confusions and negative consequences arising from this distinction.
• To argue for the elimination of the basic versus translational research dichotomy.

Main Methods:

• Historical review of research terminology.
• Conceptual analysis of current research categorization.
• Assessment of the impact of research distinctions on scientific culture and outcomes.

Main Results:

• The terms 'basic research' and 'translational research' are problematic and anachronistic.
• The current distinction leads to conceptual confusion and hinders scientific progress.
• The dichotomy between basic and translational research is contentious.

Conclusions:

• Eliminating the distinction between basic and translational research would improve scientific culture.
• A unified approach to biomedical research could enhance its effectiveness and societal impact.
• Rethinking research categorization is crucial for advancing science and its benefits.