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Reversible central neural hyperexcitability: an electroencephalographic clue to hypocalcaemia
Bhagyadhan A Patel1, Rahul T Chakor2, Kaumil V Kothari3
1Department of Neurology, T.N.M.C and B.Y.L Nair Charitable Hospital, Mumbai, Maharashtra, India.
BMJ Case Reports
|August 3, 2017
Summary
Hypocalcemia can cause cognitive decline and seizures by increasing neural excitability. Prompt correction of calcium levels reversed these neurological symptoms, avoiding unnecessary antiepileptic drug use.
Area of Science:
- Neurology
- Endocrinology
- Clinical Neurophysiology
Background:
- Hypocalcemia, a condition of low serum calcium, can manifest with diverse neurological symptoms.
- Neuromuscular hyperexcitability, indicated by Chvostek's and Trousseau's signs, is a known peripheral manifestation.
- Central nervous system effects of hypocalcemia, such as seizures and cognitive decline, require further elucidation.

