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Feedback Inhibition00:46

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Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
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In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Updated: Feb 25, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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Authors' reply

Christopher James Ryan1, Giles Newton-Howes1

  • 1Christopher James Ryan, Clinical Associate Professor and Consultation-Liaison Psychiatrist, University of Sydney and Westmead Hospital, Sydney, Australia; Giles Newton-Howes, Senior Lecturer and Consultant Psychiatrist, University of Otago, Wellington, New Zealand.

The British Journal of Psychiatry : the Journal of Mental Science
|August 3, 2017
PubMed
Summary

No abstract available in PubMed .

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