Vesicular stomatitis virus pseudotype with neutralization antigen of tick-borne encephalitis virus

Vesicular stomatitis virus (VSV), when grown in dual infection with tick-borne encephalitis (TBE) virus, produced pseudotype VSV (TBE) with surface proteins provided by TBE virus. This phenomenon can be employed in a rapid, accurate and sensitive test for detection and assay of neutralizing antibodies specific for TBE virus.