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Related Concept Videos

Intermolecular Forces03:13

Intermolecular Forces

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Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen...
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Atoms and molecules interact with each other through intermolecular forces. These electrostatic forces arise from attractive or repulsive interactions between particles with permanent, partial, or temporary charges. The intermolecular forces between neutral atoms and molecules are ion–dipole, dipole–dipole, and dispersion forces, collectively known as van der Waals forces.
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Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation
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Functional aqueous droplet networks.

Michael J Booth1, Vanessa Restrepo Schild, Florence G Downs

  • 1Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK. michael.booth@chem.ox.ac.uk hagan.bayley@chem.ox.ac.uk.

Molecular Biosystems
|August 3, 2017
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Summary
This summary is machine-generated.

Droplet interface bilayers (DIBs) enable the creation of complex 3D networks. These functional networks act as soft biodevices and hold potential for synthetic tissues.

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Area of Science:

  • Biophysics
  • Materials Science
  • Synthetic Biology

Background:

  • Droplet interface bilayers (DIBs) are lipid bilayers between aqueous droplets in oil, used for membrane protein studies.
  • Emerging research focuses on interconnected droplet networks with collective properties beyond simple pairs.

Purpose of the Study:

  • To explore the development and applications of functional 3D droplet networks.
  • To highlight advancements in droplet printing for creating complex biodevices.

Main Methods:

  • Formation of droplet interface bilayers (DIBs) in oil.
  • Development of a droplet printer for fabricating 3D patterned droplet networks.
  • Characterization of network properties, including shape changes, electrical signaling, and protein expression.

Main Results:

  • Demonstration of 2D droplet collections as soft biodevices (electronic components, light-sensors, batteries).
  • Creation of 3D droplet networks with hundreds to thousands of connected droplets using a droplet printer.
  • Exhibition of 3D networks' ability to change shape, conduct electrical signals, and express proteins under patterned illumination.

Conclusions:

  • 3D droplet networks offer novel collective properties and functionalities.
  • These networks can be engineered as autonomous synthetic tissues.
  • Potential exists for coupling these networks with living cells for tissue repair or enhancement.