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Transfusion-transmitted babesiosis leading to severe hemolysis in two patients with sickle cell anemia

Kristine Karkoska1, James Louie2, Abena O Appiah-Kubi3

  • 1Department of Pediatrics, Cohen Children's Medical Center of New York, New Hyde Park, New York.

Pediatric Blood & Cancer
|August 3, 2017
PubMed

The intracellular parasites Babesia microti and Babesia duncani can be transmitted by blood transfusion and cause severe life-threatening hemolytic anemia in high-risk patients, including those with sickle cell disease. The rarity of the diagnosis, as well as its similar clinical presentation to delayed hemolytic transfusion reaction, may lead to a delay in diagnosis, as well as inappropriate treatment with steroids or other immunosuppressive agents. The morbidity caused by this disease in especially vulnerable populations justifies the need for a universal blood-screening program in endemic areas.

Keywords:
autoimmune hemolytic anemiababesiosisblood transfusionsickle cell anemia

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