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Updated: Feb 25, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
[Intolerance glucose control in the parenteral hyperalimentation]
Ana Maria Kazue Miyadahira1, Carmen Lúcia Sfair2, Maria Sumie Koizumi3
1Auxiliar de Ensino da disciplina Enfermagem Médico-Cirúrgica I da EEUSP.
Sixty percent of non-diabetic surgical patients receiving parenteral hyperalimentation experienced glucose intolerance within the first day. Urine testing (glucosuria) proved more frequent and effective for monitoring this common complication during intravenous nutrition.
Area of Science:
- Metabolic disorders
- Clinical chemistry
- Surgical patient management
Context:
- Parenteral hyperalimentation is a critical nutritional support method for surgical patients.
- Monitoring glucose metabolism is essential during intravenous nutrition to prevent complications.
- Non-diabetic patients may still develop glucose intolerance under these conditions.
Purpose:
- To determine the incidence of glucose intolerance in non-diabetic surgical patients undergoing parenteral hyperalimentation.
- To compare the efficacy of glucosuria, reagent strip glycemia, and auto-analyzer blood sugar tests for routine monitoring.
- To identify the most suitable method for controlling glucose metabolism in this patient group.
Summary:
- Glucose intolerance was observed in 60% of patients on day one and 80% over the treatment period, defined by glucosuria or blood sugar >180mg/100 ml.
- Urine testing (glucosuria) detected glucose intolerance more frequently than blood tests due to higher testing frequency.
- Glucosuria testing is recommended for routine monitoring of patients on intravenous hyperalimentation due to its cost-effectiveness and ease of use, provided renal function is adequate.
Impact:
- Highlights the high prevalence of glucose intolerance in surgical patients receiving parenteral nutrition.
- Provides evidence-based recommendations for cost-effective and practical glucose monitoring strategies.
- Informs clinical practice regarding the management of metabolic disturbances during intensive nutritional support.
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