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Updated: Feb 25, 2026

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
Complex liver cysts in Autosomal Dominant Polycystic Kidney Disease
Zerwa Farooq1, Ashkan Heshmatzadeh Behzadi1, Jon D Blumenfeld2
1Department of Radiology, Weill Cornell Medical Center, New York, NY, United States; Department of Radiology, Columbia College of Physicians and Surgeons, New York, NY, United States.
Purpose:
To determine prevalence of complex liver cysts in Autosomal Dominant Polycystic Kidney Disease (ADPKD).
Methods:
Abdominal MRI in 186 ADPKD subjects were evaluated by two independent observers to determine prevalence of complex liver cysts.
Results:
23 (12%) of subjects, had at least 1 complex cyst. Only 8 (4%) were reported to have a complex cyst prospectively, representing an under-reporting rate of 65%. Median total cyst volume was 66-times greater for subjects with complex cysts compared to subjects without (p<0.0001).
Conclusion:
Complex hepatic cysts were observed in 12% of ADPKD cases, occurring more frequently in livers with extensive cystic involvement.
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