Related Experiment Video
Updated: Feb 25, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
HORMONAL MARKERS IN THE STUDY OF PITUITARY ADENOMAS
J R Bhardwaj1, T Somanathan2, Harsh Kumar3
1Senior Adviser (Pathology), Army Hospital, Delhi Cantt.
Abstract:
Twenty pituitary adenomas were studied using light microscopy, immunohistochemistry and electron microscopy. Based on clinical manifestations of hormonal hypersecretion they were divided into two groups, i.e. group-I (12 patients) with no endocrine dysfunction and group-II (8 patients) with endocrine dysfunction. Group-I could be further sub-divided into two groups based on IHC : group LA in which no hormone could be localised in the tissue (null cell adenomas) and group IB where hormones could be localised in the tissue (1). Tumours in group II, with light microscopy, were acidophil (n=5), basophil (n=1) or mixed (n=2) adenomas. Eight of these 20 cases were plurihormonal. Growth hormone, and prolactin were the commonest combination. This study has helped in the reclassification of the pituitary adenomas according to the hormone they produce.
More Related Videos
Related Concept Videos
Hormones of the Pituitary Gland
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
The Pituitary Gland
Major Hormones and Their Functions
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Hormones of the Adrenal Glands
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
Regulation of Hormone Secretion
Humoral...
Hypothalamic-Pituitary Axis

