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PROGNOSTIC FACTORS IN ALUMINIUM PHOSPHIDE POISONING.

R Mohanchand¹, P K Hasija², A B Pradhan³

¹Classified Specialist Medicine, 167 Military Hospital, C/o 56 APO.

Medical Journal, Armed Forces India

|August 4, 2017

Summary

Aluminium phosphide poisoning is a serious concern, particularly affecting young adults. Prompt treatment and managing shock are crucial for survival in these poisoning cases.

Keywords:

Aluminium phosphide poisoning Complications Mortality Prognostic factors

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Area of Science:

Toxicology
Emergency Medicine
Clinical Research

Background:

Aluminium phosphide (AlP) poisoning is a significant public health issue, especially in agricultural regions.
It is associated with high morbidity and mortality, posing a challenge for emergency medical services.

Purpose of the Study:

To investigate the clinical profile and outcomes of aluminium phosphide poisoning.
To identify factors influencing mortality and survival in patients with AlP poisoning.

Main Methods:

A prospective study was conducted on 12 consecutive patients with AlP poisoning.
Data collected included patient demographics, dose and type of AlP, clinical presentation, treatment, and outcomes.

Main Results:

Mortality was higher in females within the 18-36 age group.
Higher doses and fresh tablets of AlP were associated with increased fatality.
Early vomiting and prompt treatment improved outcomes, while shock duration was not predictive.
All patients presented with shock and cardiac arrhythmias; extracardiac complications were more frequent in fatal cases.

Conclusions:

Vigorous management of shock and complications can improve survival rates in AlP poisoning.
Early clinical interventions are critical for better patient outcomes.
Understanding risk factors like AlP dose and tablet freshness can aid in prognosis.