Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

520
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
520
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

555
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
555
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

649
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
649

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hybrid Quantum-Classical Model That Combines Spatial-Temporal EEG and Digitized Counterdiabatic Quantum Features for Motor Imagery Classification.

Mayo Clinic proceedings·2026
Same author

Autonomic Parameters Correlated to Acute Postoperative Pain in the Postanesthesia Care Unit: A Systematic Review.

Pain management nursing : official journal of the American Society of Pain Management Nurses·2025
Same author

An Automated Approach for Diagnosing Allergic Contact Dermatitis Using Deep Learning to Support Democratization of Patch Testing.

Mayo Clinic proceedings. Digital health·2025
Same author

Impact of Demographics and Psychological Factors on Three-Day Postoperative Pain Perception Following Hand Surgery.

Journal of clinical medicine·2025
Same author

Diagnosing Allergic Contact Dermatitis Using Deep Learning: Single-Arm, Pragmatic Clinical Trial with an Observer Performance Study to Compare Artificial Intelligence Performance with Human Reader Performance.

Dermatitis : contact, atopic, occupational, drug·2024
Same author

Sensor technology and machine learning to guide clinical decision making in plastic surgery.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2024

Related Experiment Video

Updated: Feb 25, 2026

Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration
07:44

Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration

Published on: March 18, 2016

8.7K

Future Developments in Nonsurgical Epicardial Therapies.

Christopher M Stanton1, Samuel J Asirvatham2, Charles J Bruce1

  • 1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA.

Cardiac Electrophysiology Clinics
|August 4, 2017
PubMed
Summary

The pericardium offers a unique access point for novel cardiovascular therapies, potentially enabling less invasive heart treatments. New tools for the closed pericardial space promise near-surgical cardiac access, improving patient outcomes.

More Related Videos

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens
08:57

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens

Published on: April 24, 2018

8.3K
In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart
06:31

In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart

Published on: April 27, 2016

7.8K

Related Experiment Videos

Last Updated: Feb 25, 2026

Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration
07:44

Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration

Published on: March 18, 2016

8.7K
The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens
08:57

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens

Published on: April 24, 2018

8.3K
In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart
06:31

In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart

Published on: April 27, 2016

7.8K

Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering
  • Interventional Cardiology

Background:

  • The pericardium's anatomical location provides a strategic advantage for delivering cardiovascular therapies.
  • Current therapeutic approaches often involve invasive open-heart surgery, carrying significant risks and morbidity.
  • Minimally invasive techniques are crucial for improving patient recovery and reducing healthcare burdens.

Purpose of the Study:

  • To explore the potential of the pericardial space as an access route for novel cardiovascular therapies.
  • To highlight the development of new tools for delivering therapies within the closed pericardial space.
  • To discuss emerging technologies for percutaneous cardiac interventions and stroke prevention.

Main Methods:

  • Review of anatomical advantages of the pericardium for therapeutic delivery.
  • Discussion of emerging technologies for percutaneous delivery of cardiovascular therapies.
  • Analysis of potential applications in cardiac resynchronization therapy and stroke prevention.

Main Results:

  • The pericardium serves as an ideal vantage point for novel cardiovascular therapies.
  • Development of tools for closed pericardial space therapy offers near-surgical cardiac access.
  • Epicardial leads for cardiac resynchronization therapy via percutaneous delivery show promise.
  • Left atrial appendage ligation technologies offer new stroke prevention strategies.

Conclusions:

  • The pericardium provides a promising platform for less invasive cardiovascular interventions.
  • Advancements in tools and techniques facilitate percutaneous access to the heart.
  • These innovations hold potential for improved cardiac resynchronization therapy and stroke prevention.