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Related Concept Videos

Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

679
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Increased pulse rate01:17

Increased pulse rate

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Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
1.2K
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

555
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
555
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

649
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
649
Dysrhythmias II: Classification of Tachyarrhythmias01:28

Dysrhythmias II: Classification of Tachyarrhythmias

696
Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
696
Dysrhythmias III: Characteristics of Dysrhythmias01:29

Dysrhythmias III: Characteristics of Dysrhythmias

571
Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...
571

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Don't forget the memory: Contribution of the T wave vector in localizing the site of origin of a monomorphic idiopathic ventricular tachycardia.

Journal of cardiology cases·2018
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Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-Analysis of Quality of Life, Morbidity, and Mortality.

JACC. Clinical electrophysiology·2018
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Substrate Mapping for Ventricular Tachycardia: Assumptions and Misconceptions.

JACC. Clinical electrophysiology·2018
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Anticoagulation for Cardioversion of Acute Onset Atrial Fibrillation: Time to Revise Guidelines?

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Atrial Substrate and Triggers of Paroxysmal Atrial Fibrillation in Patients With Obstructive Sleep Apnea.

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Related Experiment Video

Updated: Feb 25, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

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Tachycardia-Mediated Cardiomyopathy.

Mark E Josephson1

  • 1Cardiovascular Division, Beth Israel Deaconess Medical Center, 185 Pilgrim Road, West Baker 4, Boston, MA 02215, USA.

Cardiac Electrophysiology Clinics
|August 4, 2017
PubMed
Summary

Tachycardia-mediated cardiomyopathy is a curable heart condition. Prompt diagnosis and treatment of non-reentrant 1:2 tachycardia in a 35-year-old woman successfully resolved her congestive heart failure symptoms without requiring a heart transplant.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Heart Failure Research

Background:

  • Tachycardia-mediated cardiomyopathy (TMC) is an underrecognized cause of heart failure.
  • Unlike many cardiomyopathies, TMC is potentially reversible with appropriate intervention.
  • Early identification is crucial for effective management and improved patient outcomes.

Purpose of the Study:

  • To describe the clinical presentation, diagnostic process, and successful management of a patient with TMC.
  • To highlight the importance of electrophysiological evaluation in cases of unexplained heart failure.
  • To demonstrate a curable alternative to heart transplantation for specific cardiomyopathy cases.

Main Methods:

  • Case report of a 35-year-old woman with progressive congestive heart failure.

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Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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Last Updated: Feb 25, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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  • Electrophysiological study to identify the underlying arrhythmia.
  • Review of diagnostic criteria and treatment protocols for tachycardia-induced heart muscle disease.

    • Main Results:

    • The patient was diagnosed with a non-reentrant 1:2 tachycardia as the cause of her cardiomyopathy.
    • Successful treatment of the tachycardia led to the resolution of her heart failure symptoms.
    • The patient avoided the need for a heart transplant.

    Conclusions:

    • Tachycardia-mediated cardiomyopathy is a treatable cause of heart failure.
    • Electrophysiological assessment is vital for diagnosing and managing TMC.
    • Effective management of the underlying arrhythmia can restore cardiac function and prevent the need for advanced therapies like transplantation.