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Screening Assay for Oxidative Stress in a Feline Astrocyte Cell Line, G355-5
Published on: July 13, 2011
Cysteine, Glutathione, and Thiol Redox Balance in Astrocytes
1School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Dublin, Ireland. gethin.mcbean@ucd.ie.
Abstract:
This review discusses the current understanding of cysteine and glutathione redox balance in astrocytes. Particular emphasis is placed on the impact of oxidative stress and astrocyte activation on pathways that provide cysteine as a precursor for glutathione. The effect of the disruption of thiol-containing amino acid metabolism on the antioxidant capacity of astrocytes is also discussed.
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