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Updated: Feb 25, 2026

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Biomimetic Materials to Characterize Bacteria-host Interactions
Published on: November 16, 2015
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Utilizing an iron(iii)-chelation masking strategy to prepare mono- and bis-functionalized aerobactin analogues for
Yu-Hin Ho1, Sheng-Yang Ho1, Cheng-Chih Hsu1
1Department of Chemistry, National Taiwan University, Taipei 10617, Taiwan. wangts@ntu.edu.tw.
Abstract:
A direct and selective method for the functionalization of aerobactin has been described. Selectivity was achieved by masking the functioning carboxylate via iron-chelation, leaving the two remaining carboxylates for direct modification. Both mono- and bis-functionalized aerobactin effectively targeted pathogenic bacteria, showing a facile method with prospective applications.

