Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

968
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
968
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

1.7K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.7K
Antibiotic Selection00:57

Antibiotic Selection

60.7K
Overview
60.7K
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

762
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
762
Methods for Controlling Microbial Growth01:29

Methods for Controlling Microbial Growth

1.9K
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
1.9K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.1K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polyunsaturated fatty acids and their endocannabinoid-related metabolites activity at human TRPV1 and TRPA1 ion channels expressed in HEK-293 cells.

PeerJ·2025
Same author

Evaluating student understanding of pharmacodynamics core concepts.

European journal of pharmacology·2025
Same author

A Lactobacillus consortium provides insights into the sleep-exercise-microbiome nexus in proof of concept studies of elite athletes and in the general population.

Microbiome·2025
Same author

Slow dissociation kinetics of fentanyls and nitazenes correlates with reduced sensitivity to naloxone reversal at the μ-opioid receptor.

British journal of pharmacology·2024
Same author

Activation of CB2 Receptors by (-)-Cannabichromene but Not (+)-Cannabichromene.

Cannabis and cannabinoid research·2024
Same author

Histidine transport is essential for the growth of Staphylococcus aureus at low pH.

PLoS pathogens·2024

Related Experiment Video

Updated: Feb 25, 2026

Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry
08:51

Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry

Published on: September 15, 2020

4.7K

Microbial approaches for targeting antibiotic-resistant bacteria.

Wing Fei Wong1, Marina Santiago2

  • 1OpenBiome, 200 Inner Belt Rd, Somerville, MA, 02143, USA.

Microbial Biotechnology
|August 4, 2017
PubMed
Summary

Antibiotic resistance poses a growing threat, but understanding the gut microbiome offers new hope. Research into beneficial microbes and their mechanisms may lead to novel therapeutics against resistant bacterial infections.

More Related Videos

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

8.2K
Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance
06:42

Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance

Published on: September 27, 2024

3.0K

Related Experiment Videos

Last Updated: Feb 25, 2026

Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry
08:51

Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry

Published on: September 15, 2020

4.7K
Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

8.2K
Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance
06:42

Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance

Published on: September 27, 2024

3.0K

Area of Science:

  • Microbiology
  • Public Health
  • Infectious Diseases

Background:

  • Antibiotic-resistant bacterial infections represent a significant and escalating global health crisis.
  • Disruption of the gut microbiome by antibiotics can facilitate the colonization of antibiotic-resistant pathogens.
  • Commensal microbes play a crucial role in protecting the host from pathogenic infections, particularly within the gut.

Purpose of the Study:

  • To explore novel therapeutic strategies targeting antibiotic-resistant bacteria.
  • To discuss the role of the human microbiome in combating antibiotic resistance.
  • To highlight the potential of microbial therapeutics.

Main Methods:

  • Review of current research on gut microbiome and colonization resistance.
  • Identification of specific bacterial taxa and mechanisms involved in protection against pathogens.
  • Analysis of emerging microbial therapeutic strategies.

Main Results:

  • The human microbiome, particularly gut commensals, provides colonization resistance against pathogens.
  • Antibiotic use disrupts this protective ecosystem, increasing susceptibility to resistant strains.
  • Several research avenues are exploring microbial interventions for treating antibiotic-resistant infections.

Conclusions:

  • Harnessing the power of the gut microbiome offers a promising avenue for developing new treatments for antibiotic-resistant infections.
  • Further research into specific microbial taxa and their mechanisms is essential.
  • Overcoming challenges in microbial therapeutics is key to their clinical success.