Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cell Migration

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

"Alkaline-Hammer Strategy" Breaks Acidic and Stromal Barriers to Induce Alkaliptosis and Enhance Immunotherapy in Pancreatic Cancer.

Angewandte Chemie (International ed. in English)·2026

Same author

From single cell analysis to 3D micro physiological systems: microfluidic tools integrating cancer cell targets for delineating natural killer cell biology.

Microsystems & nanoengineering·2026

Same author

Electric fields trigger ceramide-dependent vesicle budding and boost the generation of small extracellular vesicles.

Communications biology·2026

Same author

Dynamic characterization of humidity-induced perovskite/polyacrylonitrile composite nanofibers based on tilted fiber grating.

Optics express·2026

Same author

Surface Energy Modulation of NiO<sub><i>x</i></sub> through In Situ Click-Cross-Linked Networks for Air-Processed Flexible Blue Perovskite Light-Emitting Diodes.

The journal of physical chemistry. A·2026

Same author

Differential migratory phenotypes of human neutrophils and breast cancer cells in a wireless unidirectional electric field platform.

Microsystems & nanoengineering·2026

Search research articles

Related Experiment Video

Updated: Feb 25, 2026

Study of Cell Migration in Microfabricated Channels

Study of Cell Migration in Microfabricated Channels

Published on: February 21, 2014

M_kit: A cell migration assay based on microfluidic device and smartphone.

Ke Yang¹, Jiandong Wu², Hagit Peretz-Soroka²

¹Institute of Applied Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, PR China; Department of Physics and Astronomy, University of Manitoba, Winnipeg, MB, Canada.

Biosensors & Bioelectronics

|August 4, 2017

Summary

This study introduces the M$_{kit}$, a mobile sensing (MS$^{2}$) technology for cell migration assays. This integrated kit enables easy measurement of cell chemotaxis from blood samples, with potential for clinical diagnostics.

Keywords:

Cell functional assay Cell migration Chemotaxis Microfluidic device Smartphone

More Related Videos

Assessing Neural Stem Cell Motility Using an Agarose Gel-based Microfluidic Device

Assessing Neural Stem Cell Motility Using an Agarose Gel-based Microfluidic Device

Published on: February 11, 2008

Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging

Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging

Published on: December 23, 2011

Related Experiment Videos

Last Updated: Feb 25, 2026

Study of Cell Migration in Microfabricated Channels

Study of Cell Migration in Microfabricated Channels

Published on: February 21, 2014

Assessing Neural Stem Cell Motility Using an Agarose Gel-based Microfluidic Device

Assessing Neural Stem Cell Motility Using an Agarose Gel-based Microfluidic Device

Published on: February 11, 2008

Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging

Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging

Published on: December 23, 2011

Area of Science:

Biomedical Engineering
Cell Biology
Microfluidics

Background:

Mobile sensing (MS$^{2}$) technology integrates microfluidics and smartphones for diverse applications.
MS$^{2}$ technology shows promise for cell functional assays in research and clinical settings.

Purpose of the Study:

To develop an integrated MS$^{2}$-based cell functional assay kit (M$_{kit}$) for cell migration testing.
To validate the M$_{kit}$ for measuring neutrophil and cancer cell chemotaxis.

Main Methods:

Development of an integrated kit including microfluidic chips, smartphone imaging, and analysis apps.
Assay of purified neutrophil and cancer cell chemotaxis.
Testing of whole blood samples with red blood cell (RBC) lysis for neutrophil chemotaxis.

Main Results:

The M$_{kit}$ effectively measured purified neutrophil and cancer cell chemotaxis.
Neutrophil chemotaxis was successfully assessed from whole blood samples.
The M$_{kit}$ demonstrated utility for on-site hospital testing and analysis of clinical samples from COPD patients.

Conclusions:

The M$_{kit}$ provides an accessible, integrated platform for cell migration research.
The developed system holds potential for medical diagnostic applications, particularly for on-site testing.