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MECONIUM ASPIRATION SYNDROME : A CLINICAL STUDY.

M K Behera1, S D Kulkarni2, R K Gupta3

  • 1Classified Specialist (Pediatrics), MH Secunderabad 500 015.

Medical Journal, Armed Forces India
|August 5, 2017
PubMed
Summary
This summary is machine-generated.

Meconium aspiration syndrome (MAS) affects 1.7% of newborns, with thick meconium and birth asphyxia being significant risk factors. High mortality rates underscore the need for improved neonatal care strategies for MAS.

Keywords:
Meconium aspiration syndromeMeconium stained amniotic fluid

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Area of Science:

  • Neonatalogy
  • Pediatrics
  • Obstetrics

Background:

  • Meconium aspiration syndrome (MAS) is a significant cause of neonatal morbidity and mortality.
  • Understanding the incidence and risk factors associated with MAS is crucial for effective management.

Purpose of the Study:

  • To analyze the clinical characteristics, management, and outcomes of neonates with MAS.
  • To identify potential risk factors and complications associated with MAS in a service hospital setting.

Main Methods:

  • Retrospective analysis of 42 neonates diagnosed with MAS and managed in a neonatal intensive care unit.
  • Data collected included delivery route, meconium consistency, gestational age, presence of asphyxia, seizures, pneumonia, air leak syndrome, and mortality.

Main Results:

  • The incidence of MAS was 1.7%, with 33 out of 42 cases involving thick meconium.
  • Birth asphyxia (27 cases) and seizures (13 cases) were common complications, alongside pneumonia (32 cases) and air leak syndrome (6 cases).
  • Overall mortality was 31% (13 out of 42 infants).

Conclusions:

  • Thick meconium and birth asphyxia are strongly associated with MAS and adverse outcomes.
  • The high mortality rate highlights the severity of MAS and the need for prompt and intensive neonatal care.
  • Further research into preventative strategies and optimized management protocols for MAS is warranted.