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Updated: Feb 25, 2026

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
Published on: August 1, 2018
IMPROVED ACCURACY RATES OF FNAC INTERPRETATION IN BENIGN BREAST LESIONS
G U Deshpande1, Sunita Suri2, Jaskamal3
1Reader, Armed Forces Medical College, Pune 411 040.
Abstract:
We carried out a retrospective study of 194 biopsy proved benign breast lesions comparing the fine needle aspiration cytology (FNAC) diagnosis offered earlier. We reviewed the cytology smears based on recently advocated criteria and offered our fresh diagnosis. It was observed that we still overdiagnosed five cases of fibroadenomas and underdiagnosed four cases of fibrocystic change. However the quantum of such discrepancies decreased considerably than seen earlier. We could correctly diagnose two tubular adenomas and two intraductal papillomas. We also reduced the number of nonspecific diagnosis of benign breast disease from 24 to 08. Hence we could register an overall improvement of accuracy rate to 84.5% as compared to 58.8% achieved earlier.

