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Updated: Feb 25, 2026

A Delayed Inoculation Model of Chronic Pseudomonas aeruginosa Wound Infection
Published on: February 20, 2020
[Pseudomonas aeruginosa in dermatology]
1Service de spécialités pédiatriques et de médecine infantile, hôpital de la Timone, CHU de Marseille, 264, rue Saint-Pierre, 13385 Marseille cedex 05, France.
Pseudomonas aeruginosa, a Gram-negative bacillus, causes severe skin conditions like ecthyma gangrenosum and chronic wound infections. Its antibiotic resistance necessitates specialized care for conditions such as folliculitis and chloronychia.
Area of Science:
- Microbiology
- Dermatology
- Infectious Diseases
Background:
- Pseudomonas aeruginosa is a Gram-negative bacillus known for its distinct color and odor.
- This bacterium is associated with severe dermatological conditions, particularly in immunocompromised individuals and children.
- It frequently colonizes chronic wounds, severe burns, and can manifest as spongiotic or acantholytic dermatosis.
Purpose of the Study:
- To highlight the significant dermatological impact of Pseudomonas aeruginosa infections.
- To underscore the challenges posed by Pseudomonas aeruginosa due to its antimicrobial resistance.
- To detail the various clinical presentations of Pseudomonas aeruginosa-related skin conditions.
Main Methods:
- Clinical case reviews and literature synthesis.
- Microbiological identification and characterization of Pseudomonas aeruginosa.
- Analysis of treatment challenges and resistance patterns.
Main Results:
- Pseudomonas aeruginosa can lead to severe conditions like ecthyma gangrenosum, indicating sepsis or immunosuppression.
- Colonization of chronic wounds and burns by this pathogen is common.
- Associated skin conditions include folliculitis and chloronychia, often linked to environmental exposures.
Conclusions:
- Pseudomonas aeruginosa infections require careful management due to the bacterium's inherent resistance to antibiotics and antiseptics.
- Early recognition of Pseudomonas aeruginosa-related dermatoses is crucial for timely intervention, especially in vulnerable populations.
- The diverse clinical manifestations necessitate a high index of suspicion for this opportunistic pathogen.
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