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Published on: May 8, 2015
The evolution of the Helsinki frostbite management protocol
Andrew Lindford1, Jussi Valtonen1, Maarit Hult2
1Helsinki Burn Centre, Department of Plastic Surgery, Töölö Hospital, Helsinki University Hospital, University of Helsinki, Finland.
Early intervention with tissue plasminogen activator (tPA) and iloprost significantly improved frostbite outcomes. This approach led to a high digital salvage rate, reducing the need for amputation in severe frostbite cases.
Area of Science:
- Vascular Surgery
- Emergency Medicine
- Radiology
Background:
- Severe frostbite injuries can lead to significant morbidity and loss of function, often requiring amputation.
- Traditional management of frostbite is conservative, but newer approaches involve early interventional angiography and fibrinolysis.
- This study evaluates a frostbite treatment protocol utilizing early intervention introduced three years prior.
Purpose of the Study:
- To evaluate the effectiveness of a new frostbite treatment protocol.
- To assess the outcomes of early interventional angiography and fibrinolysis in severe frostbite injuries.
Main Methods:
- Patients with frostbite underwent clinical and Doppler ultrasound examinations.
- Severe frostbite cases underwent angiography, followed by intra-arterial tissue plasminogen activator (tPA) and intravenous heparin if thrombosis was confirmed.
- Iloprost, a vasodilator, was administered intravenously in selected cases.
Main Results:
- Twenty patients were diagnosed with frostbite between 2013-2016; 14 had severe injuries.
- Ten patients underwent angiography, and nine received fibrinolytic treatment with tPA.
- The overall digital salvage rate was 74.8%, and the Hennepin tissue salvage rate was 81.1%; one patient developed a pseudoaneurysm.
Conclusions:
- Prompt referral to facilities with interventional radiology and 24/7 laboratory services is crucial.
- Combined use of tissue plasminogen activator (tPA) and iloprost may improve outcomes in severe frostbite.
- This approach offers a potential improvement over conservative management for severe frostbite.
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