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Legionella pneumophila LPS to evaluate urinary antigen tests
Anne-Gaëlle Ranc1, Margot Carpentier2, Laëtitia Beraud2
1Hospices Civils de Lyon, Centre, National de Référence des Légionelles, France; CIRI, Centre International de Recherche en Infectiologie, Université de Lyon, Lyon, France; INSERM U1111, Lyon, France Ecole Normale Supérieure de Lyon, Lyon, France; Université Lyon 1, Lyon, France; CNRS, UMR 5308, Lyon, France.
Abstract:
Three urinary antigen tests were compared using purified Legionella pneumophila (Lp) LPS. For Lp serogroup1, Sofia®FIA and Binax®EIA limits of detection (LOD) were similar; that of BinaxNOW® lower. For all tests the LOD was higher with LPS from non-Pontiac compared to Pontiac-strains. The LOD was variable for other Lp serogroups.
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