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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Early Intervention Services Improve School-age Functional Outcome Among Neonatal Intensive Care Unit Graduates
Jonathan S Litt1, M Maria Glymour2, Penny Hauser-Cram3
1Harvard School of Public Health, Boston, Mass; Harvard Medical School, Boston, Mass; Beth Israel Deaconess Medical Center, Boston, Mass.
Insights
Early intervention services significantly improve school-age functional outcomes for high-risk infants. Longer, more intense programs yield better academic and physical skills, highlighting the importance of timely referral after NICU discharge.
Area of Science:
- Pediatrics
- Developmental Psychology
- Public Health
Background:
- High-risk infants often require early intervention (EI) services to mitigate developmental delays.
- Understanding the long-term impact of EI on functional outcomes is crucial for optimizing care.
- Previous research has explored various aspects of EI, but school-age outcomes require further investigation.
Purpose of the Study:
- To evaluate the effect of community-based early intervention (EI) services on the functional outcomes of high-risk infants at school age.
- To determine if the duration, intensity, and breadth of EI services influence academic and physical skills in kindergarten.
- To assess the association between delayed EI enrollment and school-age performance.
Main Methods:
- Retrospective cohort study utilizing data from the National Early Intervention Longitudinal Study.
- Inclusion criteria: NICU admission, birth weight >400g, gestational age >23 weeks.
- Kindergarten outcomes assessed by teacher ratings; statistical analysis employed marginal structural models with inverse probability of treatment weighting to control for confounding.
Main Results:
- 47% of participants had average/above-average academic skills, and 71% had average/above-average physical skills.
- Delayed EI enrollment was associated with lower odds of average/above-average academic (aOR: 0.65) and physical skills (aOR: 0.61).
- Greater service duration, intensity, and breadth were associated with higher academic and physical skills ratings, with some associations approaching statistical significance.
Conclusions:
- Community-based early intervention services are associated with improved functional outcomes in high-risk children at school age.
- Longer, more intense, and broader EI services correlate with better kindergarten academic and physical skills.
- Findings support the effectiveness of large-scale EI programs and emphasize the importance of prompt referral after NICU discharge.
Objective:
To evaluate the effect of community-based early intervention (EI) services the on functional outcomes of high-risk infants at school age.
Methods:
This was a retrospective cohort study using data from the US Department of Education's National Early Intervention Longitudinal Study. Participants were enrolled in 1997 to 1998 with follow-up through 5 years and had a neonatal intensive care unit (NICU) admission, birth weight >400 g, and gestational age >23 weeks. Kindergarten outcomes were teacher assessments of academic and physical skills compared with classmates. Because treatment assignment is determined according to level of clinical need, we used repeated measures, marginal structural models with inverse probability of treatment weighting to account for confounding by indication.
Results:
Of 405 participants, 47% had academic ratings average/above average and 71% had physical skills ratings average/above average. Odds of average/above average academic skills were lower for those with delayed EI enrollment (adjusted odds ratio [aOR], 0.65; 95% confidence interval [CI], 0.43-0.99) and trending, although not significantly, higher for those with greater service duration (aOR, 1.47; 95% CI, 0.98-2.22) and breadth (odds ratio, 1.74; 95% CI, 0.95-3.20). Odds of average/above average physical skills were lower for those with delayed EI enrollment (aOR, 0.61; 95% CI, 0.40-0.93) and higher for those with greater intensity (aOR, 1.06; 95% CI, 1.00-1.13) and breadth (aOR, 1.86; 95% CI, 1.03-3.35), approaching significance for those with greater service duration (aOR, 1.41; 95% CI, 0.96-2.09).
Conclusions:
Longer, more intense services were associated with higher kindergarten skills ratings in children at risk for disabilities. Our novel findings support the effectiveness of large-scale EI programs and reinforce the importance of referral after NICU discharge.
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