Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

945
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
945
Surface Membrane Barriers01:18

Surface Membrane Barriers

3.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
3.1K
Biofilms01:29

Biofilms

1.6K
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
1.6K
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

1.1K
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
1.1K
Physical Methods for Controlling Microbial Growth: Radiation and Filtration01:26

Physical Methods for Controlling Microbial Growth: Radiation and Filtration

1.2K
Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
1.2K
Methods for Controlling Microbial Growth01:29

Methods for Controlling Microbial Growth

1.8K
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Atomic-Scale Charge Channelling in Poly(triazine imide) With Cooperative Ti-Ru Sites for Efficient Visible-Light CO<sub>2</sub> Reduction.

Angewandte Chemie (International ed. in English)·2026
Same author

Transient Boryl Assistance Enables Stereoselective Alkylation of Acyclic Tetrasubstituted Enolates.

Angewandte Chemie (International ed. in English)·2026
Same author

Charge-Directed Photothermal Methane Dry Reforming Enabled by Interfacial TiO<sub>x</sub> Nanodomains.

Angewandte Chemie (International ed. in English)·2026
Same author

Nickel-Catalyzed Enantioselective Hydroboration of Enamides.

Organic letters·2026
Same author

Cryo-FIB Lift-Out and Electron Tomography Workflow for Bacteria-Nanopillar Interface Imaging Under Native Conditions: Investigating Dragonfly Inspired Bactericidal Titanium Surfaces.

Small methods·2026
Same author

Decadal gelatinization and phenological advancement of small jellyfish in Laizhou Bay, Bohai Sea.

Marine pollution bulletin·2026

Related Experiment Video

Updated: Feb 25, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

4.0K

Natural and bioinspired nanostructured bactericidal surfaces.

Abinash Tripathy1, Prosenjit Sen2, Bo Su3

  • 1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK; Centre for Nano Science and Engineering, Indian Institute of Science, Bangalore 560012, India.

Advances in Colloid and Interface Science
|August 8, 2017
PubMed
Summary

Nanostructured surfaces physically rupture bacterial cell walls, offering a promising alternative to antibiotics. This approach combats rising antibiotic resistance by leveraging physical surface topography for bactericidal action.

More Related Videos

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
11:19

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

10.8K
High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

9.6K

Related Experiment Videos

Last Updated: Feb 25, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

4.0K
Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
11:19

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

10.8K
High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

9.6K

Area of Science:

  • Materials Science
  • Microbiology
  • Biotechnology

Background:

  • Rising bacterial antibiotic resistance due to overuse in healthcare and agriculture.
  • Stagnation in the development of new antibiotic drugs.
  • Limitations of chemical surface modifications for long-term antibacterial performance.

Purpose of the Study:

  • To review the bactericidal mechanisms of nanostructured surfaces.
  • To explore naturally occurring and bio-inspired surface designs.
  • To understand physical interactions between nanostructures and bacterial cell walls.

Main Methods:

  • Overview of physico-mechanical rupture of bacterial cell walls by nanostructured surfaces.
  • Analysis of parameters influencing bactericidal efficacy.
  • Summary of fabrication methods for nanostructured surfaces.

Main Results:

  • Nanostructured surfaces can achieve bactericidal action via physical cell wall rupture.
  • Bacterial specificity (Gram-positive/negative) and motility influence effectiveness.
  • Surface nanotexture parameters (size, shape, density, rigidity, chemistry) are critical.

Conclusions:

  • Physical nanostructured surfaces offer a viable strategy against antibiotic-resistant bacteria.
  • Further research into design parameters and fabrication is needed for optimized bactericidal surfaces.