Related Experiment Video
Updated: Feb 25, 2026

Grossing of Non-neoplastic Globes, Including Fetal Eyes
Published on: May 30, 2025
Common Causes of Eye Enucleation among Patients
A Farokhfar1, A Ahmadzadeh-Amiri1, M R Sheikhrezaee1
1Department of Nursing, Nasibeh Nursing and Midwifery College, Mazandaran University of Medical Sciences, Sari 48151, Mazandaran, Iran.
Background:
We investigated the contributing causes and factors leading to eye enucleation procedure among the patients referred to the ophthalmology clinic of the Center Eye Hospital in Tehran, Iran.
Patients And Methods:
We retrospectively analyzed the clinical records of patients referred to the ophthalmology clinic of the Center Eye Hospital in Tehran, Iran, in the past 3 years. The data retrieved were analyzed.
Results:
A total of 313 patients underwent eye enucleation during the past 3 years. The average age of the patients was 36.7 years (range: 20-44 years). Two hundred and eight patients (66.5%) were males and 105 (33.5%) were females. One hundred and sixty-nine patients had the right eye enucleation while 144 patients had the left eye enucleation. The various procedures included enucleation (83%), evisceration (13.4%), and exantration (3.6%). The factors leading to these procedures included trauma (33.2%), phthisis bulbi (20.7%), tumors (15.7%), and infections (10.5%).
Conclusion:
In our study population, trauma was the main factor leading to eye enucleation. Hence, measures to increase social awareness and knowledge to reduce trauma cases are necessary as a preventive approach to reduce eye enucleation procedures. Concurrently, ophthalmologists should also pay more attention in early diagnoses and screening of eye health, especially detecting tumor cases such as retinoblastoma and postsurgical care to reduce secondary infections will be effective actions to reduce the overall rate of enucleation.
Related Concept Videos
Glaucoma: Overview
Photoreceptors and Visual Pathways
Accessory Structures of the Eye
Angle Closure Glaucoma: Treatment

