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B-cell lymphoma presenting as multiple nerve sheath tumors
Jason Milton1, Julie Renner2, Victor Awuor1,2
1Grant Medical Center, Ohio Health, Columbus, USA.
Surgical Neurology International
|August 8, 2017
Summary
A rare case of Diffuse Large B-cell Lymphoma (DLBCL) in cervical nerve roots presented as radiculopathy. Surgical decompression enabled diagnosis and functional recovery, despite initial MRI findings mimicking nerve sheath tumors.
Area of Science:
- Oncology
- Neurology
- Pathology
Background:
- Diffuse Large B-cell Lymphoma (DLBCL) is the most common Non-Hodgkin lymphoma (NHL) in the US.
- Extranodal involvement occurs in about 40% of DLBCL cases.
- Cervical radiculopathy can be a rare presenting symptom of extranodal lymphoma.
Observation:
- A patient presented with cervical radiculopathy due to extranodal DLBCL in the cervical nerve roots.
- MRI findings mimicked neurofibroma or schwannoma, complicating initial diagnosis.
Findings:
- Surgical decompression provided tissue for DLBCL biopsy.
- Diagnosis of DLBCL was unexpected based on imaging characteristics.
Implications:
- Surgical intervention can be crucial for diagnosing rare extranodal lymphomas.
- Decompression may restore neurological function in affected patients.
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