Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Invasive Paget's Disease of the Breast: A Staging Pitfall Mimicking pT4 Disease.

Cureus·2026
Same author

Commentary - genetic susceptibility as a risk enhancer in secondary prevention: Contextualizing the CAD polygenic risk score.

American journal of preventive cardiology·2026
Same author

OncoGen.AI: an integrated platform for automated genomic analysis and reporting in precision oncology.

NPJ precision oncology·2026
Same author

Body weight categories and fat distribution in relation to all-cause mortality among adults with metabolic dysfunction-associated steatotic liver disease: a population-based analysis of NHANES, 2007-2018.

BMJ open·2026
Same author

Beyond a Single Pathway: LDL-C, Lipoprotein(a), and hsCRP for Life-Course ASCVD Prevention.

Journal of the American College of Cardiology·2026
Same author

High Grade B-cell Lymphoma with MYC and BCL-2 Rearrangements with a Strong Tdt and a Distinct Surface Light Chain Expression.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion·2026

Related Experiment Video

Updated: Feb 25, 2026

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
07:45

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis

Published on: January 26, 2024

2.9K

Lymph node micrometastasis in gallbladder cancer.

Swati H Shah1, Nikhil Gupta1, Gurudutt Gupta2

  • 1Department of GI Oncosurgery, Rajiv Gandhi Cancer Institute and Research Center, Sector 5, New Delhi, 110 085, India.

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|August 8, 2017
PubMed
Summary
This summary is machine-generated.

Lymph node micrometastasis in gallbladder cancer (GBC) is rare and does not impact patient outcomes. This study found a low incidence of micrometastasis, with no significant correlation to prognosis or clinicopathological factors.

Keywords:
Gallbladder cancerLymph nodesMicrometastasis

More Related Videos

High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor
09:16

High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor

Published on: June 14, 2018

10.7K
Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
06:09

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Published on: February 9, 2020

13.6K

Related Experiment Videos

Last Updated: Feb 25, 2026

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
07:45

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis

Published on: January 26, 2024

2.9K
High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor
09:16

High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor

Published on: June 14, 2018

10.7K
Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
06:09

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Published on: February 9, 2020

13.6K

Area of Science:

  • Surgical Oncology
  • Pathology
  • Gastrointestinal Cancer Research

Background:

  • Gallbladder cancer (GBC) presents a poor prognosis, even after curative surgery.
  • Lymph node metastasis is a key prognostic indicator, but distant relapses occur even without it, suggesting other factors like micrometastasis.
  • The clinical significance of lymph node micrometastasis in GBC requires further investigation.

Purpose of the Study:

  • To determine the incidence of lymph node micrometastasis in gallbladder cancer patients.
  • To evaluate the clinical significance and prognostic value of lymph node micrometastasis.

Main Methods:

  • Prospective study of 40 patients undergoing curative surgery for GBC.
  • Examination of 589 lymph nodes using hematoxylin and eosin and CK7 immunohistochemistry.
  • Correlation analysis of micrometastasis with clinicopathological parameters, recurrence, and survival.

Main Results:

  • Metastasis was observed in 2.20% of nodes (8/40 patients), and micrometastasis in 0.68% of nodes (3/40 patients).
  • Micrometastases were absent in pT1 tumors and more frequent in patients with nodal metastasis.
  • Despite potentially upstaging the disease, micrometastasis did not significantly correlate with clinicopathological factors, recurrence, or survival.

Conclusions:

  • The incidence of lymph node micrometastasis in gallbladder cancer is low.
  • Micrometastasis in GBC does not appear to correlate with clinicopathological parameters, recurrence, or survival.