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One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
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One of the common methods to prepare nitriles is the dehydration of amides. This method requires strong dehydrating agents like phosphorous pentoxide or boiling acetic anhydride for converting amides to nitriles. Another reagent namely, thionyl chloride also accomplishes the dehydration of amides, where amide acts as a nucleophile. The first step of the mechanism involves the nucleophilic attack by the amide on the thionyl chloride to form an intermediate. In the next step, the electron pairs...
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In organic synthesis, the formation of products can be altered by changing the reaction conditions. For example, a dibromo addition product is formed when propene is treated with bromine at room temperature. In contrast, propene undergoes allylic substitution in non-polar solvents at high temperatures to give 3-bromopropene. In order to avoid the addition reaction, the bromine concentration must be kept as low as possible throughout the reaction. This can be achieved using N-bromosuccinimide...
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A Convenient Route to Mixed Pnictogenylboranes.

Oliver Hegen1, Christian Marquardt1, Alexey Y Timoshkin2

  • 1Universität Regensburg, Institut für Anorganische Chemie, 93040, Regensburg, Germany.

Angewandte Chemie (International Ed. in English)
|August 8, 2017
PubMed
Summary

Researchers synthesized novel mixed pnictogenylboranes, creating Lewis acid/base stabilized butane analogues. These compounds, featuring phosphorus, arsenic, and antimony, were fully characterized, offering new insights into inorganic chemistry.

Keywords:
antimonyarsenicboronmolecular chainsphosphorus

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Area of Science:

  • Inorganic Chemistry
  • Organometallic Chemistry
  • Materials Science

Background:

  • The synthesis of novel compounds with unique bonding arrangements is crucial for advancing chemical understanding.
  • Lewis acid/base stabilized compounds offer tunable properties and potential applications in catalysis and materials.

Purpose of the Study:

  • To synthesize and characterize novel mixed pnictogenylboranes.
  • To investigate the formation of Lewis acid/base stabilized butane analogues.
  • To explore the structural and electronic properties of these new compounds.

Main Methods:

  • Synthesis of mixed pnictogenylboranes via substitution reactions.
  • Characterization using single-crystal X-ray diffraction, mass spectrometry, NMR, and IR spectroscopy.
  • Computational analysis using Density Functional Theory (DFT) for thermodynamic insights.

Main Results:

  • Successful synthesis of Lewis acid/base stabilized butane analogues incorporating phosphorus, arsenic, and antimony.
  • Structural elucidation of new compounds, revealing unique bonding and coordination.
  • Characterization data confirmed the formation and stability of the target molecules.
  • DFT calculations provided thermodynamic data for the observed reactions.

Conclusions:

  • The study successfully synthesized and characterized a series of novel mixed pnictogenylboranes.
  • The findings demonstrate the feasibility of creating Lewis acid/base stabilized butane analogues with diverse pnictogen elements.
  • This work expands the scope of known pnictogenylborane chemistry and provides a foundation for future research in this area.