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Candida auris: a worrisome, globally emerging pathogen

Bhagyashri D Navalkele1, Sanjay Revankar2, Pranatharthi Chandrasekar3

  • 1a Infection Prevention and Antimicrobial Stewardship Fellow, Division of Infectious Diseases , Wayne State University/Detroit Medical Center , Detroit , MI , USA.

Expert Review of Anti-Infective Therapy
|August 8, 2017
PubMed
Abstract

Insights

Candida auris is a challenging, multidrug-resistant fungal pathogen causing hospital-acquired infections with high mortality. Early diagnosis and infection control are crucial for managing this emerging threat.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Hospital Epidemiology

Background:

  • Candida auris is a novel fungal pathogen causing serious hospital-acquired infections.
  • These infections are characterized by multidrug resistance and high mortality rates.
  • The rapid emergence of Candida auris presents a significant global health concern.

Purpose of the Study:

  • To review the epidemiology, pathogenesis, and clinical presentation of Candida auris infections.
  • To discuss diagnostic challenges and current treatment strategies.
  • To highlight infection prevention and outbreak management measures.

Main Methods:

  • Literature review of epidemiology, pathogenesis, clinical presentation, diagnostics, and treatment.
  • Analysis of infection prevention and outbreak control strategies.
  • Expert commentary on the challenges posed by Candida auris.

Main Results:

  • Candida auris infections are hospital-acquired, multidrug-resistant, and have high mortality.
  • Early diagnosis and effective infection prevention are critical for patient outcomes.
  • Limited diagnostic availability and treatment options complicate management.

Conclusions:

  • The rapid emergence of hospital-onset Candida auris is a major concern.
  • Improved diagnostic methods and treatment options are urgently needed.
  • Further research is essential to understand and combat this difficult-to-treat pathogen.
Keywords:
C. aurisCandidaCandidemiaFungal infectionbloodstream infection

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