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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

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IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
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Secondary Lymphoid Organs01:15

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Nephrotic Syndrome III : Nursing Management01:24

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Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
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Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
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Sjögren's syndrome.

Iona Thorne1, Nurhan Sutcliffe2

  • 1Specialist Registrar, Department of Rheumatology, Imperial College Healthcare NHS Trust, London W12 0HS.

British Journal of Hospital Medicine (London, England : 2005)
|August 8, 2017
PubMed
Summary

This review covers Sjögren

Area of Science:

  • Rheumatology and Immunology
  • Autoimmune Diseases

Background:

  • Sjögren's syndrome is a chronic autoimmune disorder.
  • It primarily affects exocrine glands, leading to dryness.
  • Systemic manifestations can impact various organs.

Purpose of the Study:

  • To review key aspects of Sjögren's syndrome diagnosis and management.
  • To highlight recent advancements in the field.
  • To provide a comprehensive overview for clinicians and researchers.

Main Methods:

  • Literature review of recent studies and clinical guidelines.
  • Synthesis of information on clinical presentation, diagnostic criteria, and therapeutic options.
  • Analysis of emerging trends in prognostication and treatment.

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Main Results:

  • Comprehensive summary of clinical features.
  • Discussion of current diagnostic approaches and challenges.
  • Overview of updated management strategies and novel treatments.

Conclusions:

  • Accurate diagnosis and timely management are crucial for Sjögren's syndrome.
  • Recent developments offer improved prognostication and treatment options.
  • Continued research is vital for advancing patient care.