Hyperbaric oxygen therapy for wound breakdown after oronasal fistula and cleft palate repair: four cases

C Lane Anzalone1, Cara C Cockerill1, Shelagh A Cofer1

  • 1Department of Otorhinolaryngology, Mayo Clinic, Rochester, Minnesota, U.S.

Insights

Hyperbaric oxygen (HBO) therapy shows promise for treating early surgical wound breakdown following cleft palate repair in children. This therapy helped reduce fistula size and improve wound healing in a small patient group.

Area of Science:

  • Pediatric Surgery
  • Wound Healing
  • Oxygen Therapy

Background:

  • Cleft palate repair can lead to oronasal fistulas and wound breakdown.
  • Early intervention is crucial for successful surgical outcomes in pediatric patients.

Observation:

  • Four pediatric patients with early surgical wound breakdown after cleft palate repair were treated with hyperbaric oxygen (HBO) therapy.
  • HBO therapy was initiated promptly upon identification of oronasal fistulas.

Findings:

  • All patients received 10-11 HBO treatments without adverse effects.
  • Significant reduction in fistula size and development of granulation tissue at wound edges were observed.
  • HBO therapy appeared to salvage portions of the surgical repair.

Implications:

  • Hyperbaric oxygen therapy may be an effective adjunctive treatment for wound breakdown post-cleft palate repair.
  • Early initiation of HBO therapy is associated with positive outcomes in pediatric wound healing.
  • Further research is warranted to confirm these preliminary findings in larger cohorts.

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