Recent advances in vitamins analysis by capillary electrophoresis

Area of Science:

• Analytical Chemistry
• Biochemistry

Background:

• Vitamins are vital for human metabolism, impacting energy, immunity, and cell formation.
• Precise vitamin quantification is essential for diagnostics, nutritional evaluation, and quality control in food and pharmaceuticals.

Purpose of the Study:

• To review recent developments in capillary electrophoresis (CE) for vitamin analysis.
• To cover advancements from mid-2007 to mid-2017, focusing on separation modes and detection techniques.

Main Methods:

• Review of scientific literature on capillary electrophoresis applications for vitamin analysis.
• Discussion of various CE separation modes for water- and fat-soluble vitamins.
• Exploration of on-line sample concentration techniques for enhanced sensitivity.

Main Results:

• Significant progress in CE techniques for comprehensive vitamin profiling.
• Effective separation strategies for diverse vitamin types (water- and fat-soluble).
• Demonstrated utility of on-line concentration for trace-level vitamin detection.

Conclusions:

• Capillary electrophoresis offers a versatile and sensitive platform for vitamin analysis.
• CE methods are applicable across pharmaceutical, dietary supplement, and biological sample matrices.
• Continued advancements in CE enhance its role in nutritional and clinical science.