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Horizontal Gel Electrophoresis for Enhanced Detection of Protein-RNA Complexes

Megan E Dowdle1, Susanne Blaser Imboden1, Sookhee Park1

  • 1Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health.

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Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
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Protein Complex Assembly

No description available
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