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Related Experiment Video

Updated: Feb 25, 2026

Proteomic Analysis of Human Macrophage Polarization Under a Low Oxygen Environment

Proteomic Analysis of Human Macrophage Polarization Under a Low Oxygen Environment

Published on: January 7, 2019

AOD: the antioxidant protein database.

Pengmian Feng¹, Hui Ding², Hao Lin³

¹Hebei Province Key Laboratory of Occupational Health and Safety for Coal Industry, School of Public Health, North China University of Science and Technology, Tangshan, 063000, China.

Scientific Reports

|August 9, 2017

Summary

This summary is machine-generated.

Researchers can now access the Antioxidant Database (AOD), a new resource detailing antioxidant proteins and their functions. This database aids in understanding how antioxidants protect organisms from free radical damage.

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Last Updated: Feb 25, 2026

Proteomic Analysis of Human Macrophage Polarization Under a Low Oxygen Environment

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Area of Science:

Biochemistry
Molecular Biology
Bioinformatics

Background:

Antioxidants are crucial molecules preventing cellular damage from free radicals.
Existing resources lack a specialized database for antioxidant proteins.
Understanding antioxidant functions is vital for biological research.

Purpose of the Study:

To develop a comprehensive database for antioxidant proteins.
To facilitate research on the biological functions of antioxidants.
To provide a centralized resource for antioxidant protein data.

Main Methods:

Developed the Antioxidant Database (AOD).
Extracted data from UniProtKB/Swiss-Prot.
Integrated sequence similarity search and identification tools.

Main Results:

AOD currently contains 710 antioxidant proteins.
Includes data on taxonomy, subcellular location, gene ontology, and function.
Offers integrated bioinformatics tools for analysis.

Conclusions:

AOD provides a valuable, freely accessible resource for antioxidant research.
The database and integrated tools will accelerate studies on antioxidant proteins.
AOD is expected to significantly advance the understanding of antioxidant functions.