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Updated: Feb 25, 2026
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Mushroom-Like Skin Tumours: Report of Three Cases
Uwe Wollina1, Dana Langer1, Georgi Tchernev2
1Department of Dermatology and Allergology, Academic Teaching Hospital Dresden Friedrichstadt, 01067 Dresden, Germany.
Abstract:
Mushroom like the growth of skin tumour is a rare phenomenon although described already in 1806 by Alibert, who focused on mycosis fungicides. We identified only four case reports in PUBMED database using the terms "mushroom-like growth" and "skin tumour". We analysed our files and identified three elderly female patients (69 to 94 years old). Histological diagnosis was melanoma, Merkel cell carcinoma and basal cell carcinoma. All tumours could be completely removed by wide excision or delayed Mohs surgery. No metastatic spread was noted.
Insights
Mushroom-like skin tumors are rare, with only four prior reports. This study identified three new cases of melanoma, Merkel cell carcinoma, and basal cell carcinoma in elderly women, all successfully treated with surgery.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Mushroom-like growth of skin tumors is a rare phenomenon, first described in 1806.
- Literature search revealed only four previous case reports of mushroom-like skin tumors.
Purpose of the Study:
- To report on additional cases of mushroom-like skin tumors.
- To analyze the clinical and histological characteristics of these rare tumors.
Main Methods:
- Retrospective analysis of patient files.
- Literature search using terms "mushroom-like growth" and "skin tumor" in the PUBMED database.
- Histopathological examination of tumor samples.
Main Results:
- Three elderly female patients (ages 69-94) with mushroom-like skin tumors were identified.
- Histological diagnoses included melanoma, Merkel cell carcinoma, and basal cell carcinoma.
- All tumors were completely removed via wide excision or delayed Mohs surgery, with no metastatic spread observed.
Conclusions:
- Mushroom-like growth can occur in various skin malignancies, including melanoma, Merkel cell carcinoma, and basal cell carcinoma.
- Surgical excision is an effective treatment for these rare tumors.
- Early detection and complete removal are crucial to prevent metastasis.
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