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Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
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The Role of Cardiovascular Magnetic Resonance Imaging in Heart Failure

Mark A Peterzan1,2, Oliver J Rider2, Lisa J Anderson1

  • 1Cardiology Clinical Academic GroupSt George's Hospital, London, UK.

Cardiac Failure Review
|August 9, 2017
PubMed

Insights

Cardiovascular magnetic resonance imaging is crucial for diagnosing heart failure and identifying its causes. This imaging technique offers accurate, radiation-free assessments of heart function and tissue, aiding in treatment decisions.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Cardiovascular Diseases

Background:

  • Cardiovascular imaging is essential for managing heart failure patients.
  • Cardiovascular magnetic resonance imaging (CMR) is established for assessing heart failure syndromes and identifying etiology.
  • The roles of CMR in prognosis and guiding therapy are expanding.

Purpose of the Study:

  • To highlight the established and emerging roles of cardiovascular magnetic resonance imaging in heart failure assessment.
  • To detail the key strengths of CMR in evaluating cardiac function and tissue characteristics.
  • To discuss the specific applications of CMR in conditions like iron overload cardiomyopathy, cardiac amyloidosis, and Anderson-Fabry disease.

Main Methods:

  • Utilizes cardiovascular magnetic resonance imaging (CMR).
  • Employs techniques such as T2* for iron overload assessment and T1 for specific disease therapies.
  • Assesses left and right ventricular volumes, myocardial tissue, thrombus, and scar.

Main Results:

  • CMR provides accurate and reproducible assessments of cardiac structure and function.
  • It offers a radiation-free imaging modality with an unrestricted field of view.
  • CMR excels in characterizing myocardial tissue, thrombus, and scar, and in assessing ventricular volumes.

Conclusions:

  • Cardiovascular magnetic resonance imaging is a vital tool in the comprehensive assessment of heart failure.
  • Its established role in etiology identification and emerging applications in prognosis and therapy guidance underscore its importance.
  • Specific CMR sequences like T2* and T1 are crucial for managing conditions such as iron overload cardiomyopathy and specific genetic heart diseases.

Keywords:
Cardiovascular magnetic resonanceT1 mappingT2*cardio-oncologycardiomyopathydelayed enhancementheart failurelate gadolinium enhancementmyocarditisprognosis

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