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Updated: Feb 25, 2026

Indirect Immunofluorescence on Frozen Sections of Mouse Mammary Gland
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Breast hibernomas: Questioning the embryological origin?

Carol-Ann Benn1,2, Kirsten Coetzee2, Sarah Rayne1,2

  • 1Helen Joseph Hospital Breast Care Clinic, Department of Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

The Breast Journal
|August 9, 2017
PubMed
Summary

This review discusses hibernomas, a rare brown fat tumor, in the breast. Surgical removal is effective, even for large tumors, with good cosmetic outcomes without complex oncoplastic procedures.

Keywords:
brown adipose tissueembyrologyhibernoma

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Area of Science:

  • Surgical Oncology
  • Pathology
  • Radiology

Background:

  • Hibernomas are benign tumors composed of brown adipose tissue.
  • Their occurrence in the breast is rare, prompting further investigation into their origin.

Observation:

  • A case study from Johannesburg, South Africa, details a patient's clinical, radiological, and pathological findings.
  • The patient presented with a rapidly growing breast mass.

Findings:

  • Hibernomas exhibit distinct features on clinical examination, imaging, and pathology.
  • Surgical excision is the primary treatment, with successful outcomes and minimal scarring.
  • The origin of breast hibernomas (breast tissue vs. underlying muscle) is discussed.

Implications:

  • This review provides guidance on surgical approaches for large hibernomas, emphasizing cosmetic results.
  • Understanding hibernoma characteristics aids in accurate diagnosis and appropriate management, distinguishing them from malignant breast lesions.