[Evaluation of enzyme modules of the Beckman Astra 8]

We evaluated the analytical performances of the Beckman Astra 8 enzyme analyser which allows the determination of the 6 enzymes (creatine kinase, Aspartate aminotransferase, Alanine aminotransferase, gamma glutamyl-transferase, lactate dehydrogenase, Alcaline Phosphatases), in a same serum sample with only two modules. We compared the results obtained in the healthy and pathological subject's sera with those given by a centrifugal analyser IL Multistat III (Delhomme) using reagents and temperature recommended by SFBC (Société Française de Biologie Clinique). Instrument utilization is greatly helped by various alarms and diagnostic programmes. Results for emergency and routine determinations accord with those announced by the manufacturer and those required for a modern enzymatic analyzer.