Hypertension in people living with HIV

Rosan A van Zoest1, Bert-Jan H van den Born, Peter Reiss

  • 1aDepartment of Global Health, Academic Medical Center, and Amsterdam Institute for Global Health and Development, Amsterdam Health Technology Center bDepartment of Internal Medicine, Division of Vascular Medicine cDepartment of Internal Medicine, Division of Infectious Diseases, Amsterdam Infection and Immunity Institute, Academic Medical Center dHIV Monitoring Foundation, Amsterdam, The Netherlands.

Insights

Hypertension is a significant health concern for people living with HIV (PLHIV), with higher prevalence than in the general population. Improving hypertension management is crucial for their cardiovascular health and quality of life.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Hypertension is a growing concern in the HIV-positive population.
  • The prevalence of hypertension in people living with HIV (PLHIV) may exceed that in HIV-negative individuals.

Purpose of the Study:

  • To review the current understanding of hypertension burden in PLHIV.
  • To explore risk factors and clinical management strategies for hypertension in PLHIV.

Main Methods:

  • Literature review of existing studies on hypertension in PLHIV.
  • Analysis of risk factors, including demographic, genetic, lifestyle, and treatment-related elements.
  • Examination of clinical management challenges, focusing on drug interactions.

Main Results:

  • Hypertension is highly prevalent in PLHIV, influenced by multiple factors like obesity, ART, and immune activation.
  • Key risk factors include demographics, genetics, lifestyle, comorbidities, and antiretroviral therapy (ART).
  • Suboptimal awareness, treatment, and control of hypertension in PLHIV necessitate improvement.

Conclusions:

  • The multifactorial pathophysiology of hypertension in PLHIV requires further elucidation for targeted interventions.
  • Improving hypertension management according to current guidelines is essential for safeguarding cardiovascular health and quality of life in PLHIV.
Abstract

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