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Related Concept Videos

Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules01:18

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Bioequivalence in generic drugs, such as tablets and capsules, refers to their pharmaceutical equivalence to the brand-name counterparts. However, for therapeutic equivalence, manufacturers must also consider physical attributes like size, shape, and weight (FDA Guidance for Industry, December 2003). Discrepancies in these aspects could impact patient compliance and cause medication errors. For instance, swallowing difficulties, often experienced with larger tablets or capsules, can lead to...
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Biopharmaceutical Factors Influencing Drug Product Design: Overview01:22

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Rational drug product design integrates knowledge of the drug’s physicochemical properties, formulation components, manufacturing techniques, and intended route of administration. Each factor influences the drug’s performance, including how it is released, absorbed, and eliminated in the body.The physicochemical properties of a drug—such as solubility, stability, and particle size—affect its compatibility with excipients and the choice of dosage form. Excipients, though...
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Clinically Relevant Drug Product Specifications: Methods of Establishment01:29

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Product specifications define the acceptable quality of a pharmaceutical product by ensuring identity, purity, potency, and strength. These specifications serve as benchmarks during development, manufacturing, and post-approval quality control. Clinically relevant specifications are particularly important because they directly relate to a drug's safety and efficacy in clinical use.Dissolution studies are critical biopharmaceutic tools that link in vitro behavior to in vivo performance. They...
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Biopharmaceutics and Pharmacokinetics: Overview01:28

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Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
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Drug Dosage Regimen: Overview01:15

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A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
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Pharmaceutical Poisoning: Potential Scenarios01:26

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Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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Related Experiment Video

Updated: Feb 25, 2026

Improving IV Insulin Administration in a Community Hospital
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Implementation of a formulary management process.

Lauren I Karel1, Dennis R Delisle2, Ellena A Anagnostis3

  • 1Department of Pharmacy, Thomas Jefferson University Hospital, Philadelphia, PA. lauren.karel@jefferson.edu.

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
|August 10, 2017
PubMed
Summary
This summary is machine-generated.

Lean methodology streamlined hospital formulary management. This initiative standardized processes for medication additions and deletions, improving efficiency and communication within the pharmacy department for better drug management.

Keywords:
formularieshospitallean methodologypharmacy and therapeutics committeequality improvement

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Area of Science:

  • Health Systems Management
  • Pharmacy Practice
  • Process Improvement

Background:

  • Hospital formulary maintenance is complex, requiring coordination among pharmacy department members.
  • Optimizing formulary management is crucial for safe and efficient medication use.

Purpose of the Study:

  • To describe the application of lean methodology in redesigning the formulary maintenance process.
  • To optimize formulary management systemwide within a multihospital health system.

Main Methods:

  • Established a formulary maintenance redesign committee with diverse pharmacy expertise.
  • Utilized lean principles, including value stream analysis and kaizen events, for process improvement.
  • Developed standardized templates for monographs and a shared Web-based checklist for task management.

Main Results:

  • Identified opportunities for process and performance improvement through value stream analysis.
  • Gathered staff suggestions for streamlining the formulary management process.
  • Created standardized tools to facilitate information sharing and timely completion of formulary changes.

Conclusions:

  • A standardized process for tracking formulary changes was developed.
  • The initiative aimed to enhance workflow safety and efficiency in the pharmacy department.
  • Continuous monitoring and refinement of the formulary management process were established.