Related Experiment Video
Updated: Feb 25, 2026

Normothermic Ex Situ Heart Perfusion in Working Mode: Assessment of Cardiac Function and Metabolism
Published on: January 12, 2019
[Perioperative Care of Low Cardiac Output Syndrome]
1Department of Cardiovascular and Thoracic Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Abstract:
Low cardiac syndrome( LOS) is the imbalance of the oxygen supply and demand at the tissue due to reduced oxygen supply by decreased cardiac function. The causes of the cardiac dysfunction are insufficient cardioplegia, elongation of aortic clamp or cardiopulmonary bypass (CPB) duration, incomplete revascularization, and so on. The preventions of LOS are myocardial protections intraoperatively. The most important myocardial protection is to accomplish more quickly, accurately and safety to operation. And today, cardioplegia is essential for surgery requiring CPB. The integrated myocardia protection is likely to be effective to the patients who suffer low cardiac function. LOS is commonly defined the decreased cardiac index (CI)[<2.0~2.2 l/min/m2], systolic blood pressure (<80~90 mmHg) and the signs of tissue malperfusion, in the absence of hypovolemia. The treatment of LOS is, at first, the correction of hypovolemia, then rhythm control, adjustment of preload and afterload. When it does not recover from LOS despite adequate treatment, the mechanical circulatory assist devices should be introduced without hesitation.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiopulmonary Resuscitation IV: Pharmacological Management
Acute Coronary Syndrome V: Nursing Management
Cardiomyopathy VI: Nursing Management
Acute Coronary Syndrome IV: Interprofessional Care
Heart Failure VII: Nursing Interventions

