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Related Concept Videos

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Related Experiment Video

Updated: Feb 25, 2026

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
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GRAVES' DISEASE WITH ORGANIC MOOD SYNDROME (A Case Report).

Hra Prabhu1, T K Jagdish2, P S Valdiya3

  • 1Classified Specialist (Psychiatry), Command Hospital (SC), Pune - 411040 (Maharashtra).

Medical Journal, Armed Forces India
|August 10, 2017
PubMed
Summary
This summary is machine-generated.

This case report details a 30-year-old man with Graves disease who developed mania. Antipsychotic medication was required to manage these severe mood symptoms.

Keywords:
Graves' diseaseMania

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Area of Science:

  • Endocrinology
  • Psychiatry
  • Neuroscience

Background:

  • Graves' disease is an autoimmune disorder causing hyperthyroidism.
  • Hyperthyroidism can manifest with psychiatric symptoms, including mood disturbances.
  • Organic mood syndrome refers to mood changes caused by a medical condition.

Observation:

  • A 30-year-old male patient with diagnosed Graves' disease was admitted to the hospital.
  • During hospitalization, the patient exhibited symptoms consistent with mania.
  • The manic symptoms required intervention with antipsychotic medications.

Findings:

  • The patient's thyrotoxicosis was associated with the development of an organic mood syndrome.
  • Manic features emerged as a direct consequence of the hyperthyroid state.
  • Antipsychotic therapy was necessary to manage the acute manic episode.

Implications:

  • This case underscores the critical link between endocrine dysfunction and psychiatric manifestations.
  • Clinicians should consider thyrotoxicosis in the differential diagnosis of new-onset mania or mood disorders.
  • Effective management of underlying Graves' disease may be crucial for resolving psychiatric symptoms.