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Updated: Feb 25, 2026

Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
Published on: January 26, 2018
VALETHEMATE BROMIDE AND CERVICAL DILATATION
A D Dwivedi1, G Rai1, S Sharda2
1Classified Specialist (Obstetrics & Gynaecology), Military Hospital, Ambala Cantt.
Abstract:
The importance of cervical dilatation in normal labour is well known & cervical dystocia is known to prolong labour adversely affecting fetomaternal well being. Valethemate bromide(Injection Epidosin) has been known to shorten the first stage of labour & several studies have proved the efficacy of this drug. Injection Epidosin was used on five hundred patients (250 Primigravida and 250 multiparas) having uncomplicated labour and its efficacy in shortening the first stage of labour was studied. This study proved that epidsosin could reduce first stage of labour in primigravidas as well as multiparas significantly without any major side effects and could be used safely under supervision of a nursing staff.
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