Free radicals, lipid peroxidation, and Parkinson's disease

An NLRP3 inflammasome inhibitor evoked dose-dependent anti-allodynia in the hindpaws of a rat model of chemotherapy-induced peripheral neuropathy.

Inflammopharmacology·2026

The High-Energy Ion Telescope (HIT) for the Interstellar Mapping And Acceleration Probe (IMAP) Mission.

Space science reviews·2026

Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain.

Frontiers in pharmacology·2025

The angiotensin II type 2 receptor antagonists, PD123,319 ((S-( +)-1-[(4-(dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid), EMA300 (5-(2,2-diphenylacetyl)-4-[(4-methoxy-3-methylphenyl)methyl]-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-6-carboxylic acid) and EMA401 ((3S)-5-(benzyloxy)-2-(2,2-diphenylacetyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid), evoke pain relief in a varicella zoster virus-induced rat model of neuropathic pain.

Inflammopharmacology·2025

J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine.

Frontiers in pharmacology·2024

Prostate cancer induced bone pain: pathobiology, current treatments and pain responses from recent clinical trials.

Discover oncology·2022

Safety and lipoprotein(a)-lowering effects of Kylo-11, a non-canonical, long-duration small interfering RNA targeting lipoprotein(a): a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial.

Lancet (London, England)·2026

Generalised eruptive histiocytosis mimicking lymphoma relapse in a patient with previous diffuse large B-cell lymphoma.

Lancet (London, England)·2026

Physiotherapist-led care for musculoskeletal conditions in the emergency department (RESHAP-ED): a randomised controlled trial with economic evaluation.

Lancet (London, England)·2026

Systematic reviews and the needs of the adolescent transgender health care field.

Lancet (London, England)·2026

Pre-eclampsia.

Lancet (London, England)·2026

Aryl hydrocarbon receptor as a molecular mediator in the induction of human aldehyde oxidase gene expression.

The Journal of pharmacology and experimental therapeutics·2026

Colorimetric detection of H2O2 based on the synergistic catalytic enhancement effect of Fe3O4@NH2-MIL-88B.

Analytical methods : advancing methods and applications·2026

Circularly polarized electroluminescence from topologically chiral [2]catenane-based neutral radicals with tunable deep-red emission.

Nature communications·2026

Synthesis of Chiral-at-Sulfur(VI) Sulfonimidamide Brønsted Acids.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026

Deaminative C(sp3)-C(sp2) and C(sp3)-S coupling of alkylamines.

Chemical communications (Cambridge, England)·2026

TiO2‑Mediated Enamine Radical Cation Cycloadditions: Divergent [4 + 2] and [2 + 2] Reactivity.

Precision chemistry·2026

Related Experiment Videos

Free radicals, lipid peroxidation, and Parkinson's disease

Related Concept Videos

An NLRP3 inflammasome inhibitor evoked dose-dependent anti-allodynia in the hindpaws of a rat model of chemotherapy-induced peripheral neuropathy.

The High-Energy Ion Telescope (HIT) for the Interstellar Mapping And Acceleration Probe (IMAP) Mission.

Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain.

J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine.

Prostate cancer induced bone pain: pathobiology, current treatments and pain responses from recent clinical trials.

Safety and lipoprotein(a)-lowering effects of Kylo-11, a non-canonical, long-duration small interfering RNA targeting lipoprotein(a): a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial.

Generalised eruptive histiocytosis mimicking lymphoma relapse in a patient with previous diffuse large B-cell lymphoma.

Physiotherapist-led care for musculoskeletal conditions in the emergency department (RESHAP-ED): a randomised controlled trial with economic evaluation.

Systematic reviews and the needs of the adolescent transgender health care field.

Pre-eclampsia.

Aryl hydrocarbon receptor as a molecular mediator in the induction of human aldehyde oxidase gene expression.

Colorimetric detection of H2O2 based on the synergistic catalytic enhancement effect of Fe3O4@NH2-MIL-88B.

Circularly polarized electroluminescence from topologically chiral [2]catenane-based neutral radicals with tunable deep-red emission.

Synthesis of Chiral-at-Sulfur(VI) Sulfonimidamide Brønsted Acids.

Deaminative C(sp3)-C(sp2) and C(sp3)-S coupling of alkylamines.

TiO2‑Mediated Enamine Radical Cation Cycloadditions: Divergent [4 + 2] and [2 + 2] Reactivity.

Related Experiment Videos

Free radicals, lipid peroxidation, and Parkinson's disease

Related Concept Videos

Related Articles