Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

1.7K
Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
1.7K
Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

921
Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
921
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

17.2K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
17.2K
Overview of Electron Microscopy01:25

Overview of Electron Microscopy

15.7K
The wavelengths of visible light ultimately limit the maximum theoretical resolution of images created by light microscopes. Most light microscopes can only magnify 1000X, and a few can magnify up to 1500X. Electrons, like electromagnetic radiation, can behave like waves, but with wavelengths of 0.005 nm, they produce significantly greater resolution up to 0.05 nm as compared to 500 nm for visible light. An electron microscope (EM) can create a sharp image that is magnified up to 2,000,000X.
15.7K
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

11.6K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
11.6K
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

14.6K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
14.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Binding Mechanism of UAMC-1110 to Fibroblast Activation Protein.

Journal of chemical information and modeling·2026
Same author

Mechanism of Polyester Hydrolysis by Marine Bacterium PE-H Enzyme: an Atomistic and Thermodynamic Characterization.

Journal of chemical information and modeling·2026
Same author

Mechanism of Hyaluronic Acid Hydrolysis Catalyzed by Snake Venom Hyaluronidase.

Journal of chemical information and modeling·2026
Same author

Mechanistic insights into NOBA hydrolysis by viper venom secreted phospholipase A<sub>2</sub>.

Biochimie·2025
Same author

The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

Revealing the rationale behind the differential neutralization of phospholipase A<sub>2</sub> (PLA<sub>2</sub>) enzymes in snake and bee venom by varespladib (LY-315920), a small molecule PLA<sub>2</sub> inhibitor.

Journal of biomolecular structure & dynamics·2025

Related Experiment Video

Updated: Feb 25, 2026

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy
11:26

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy

Published on: September 8, 2009

9.9K

Visualizing the Microscopic World.

Nuno M F S A Cerqueira1, Pedro A Fernandes2, Maria João Ramos2

  • 1UCIBIO@REQUIMTE, Departamento de Química e Bioquímica da Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre, s/n, Porto, 4169-007, Proto, Portugal. nscerque@fc.up.pt.

Interdisciplinary Sciences, Computational Life Sciences
|August 10, 2017
PubMed
Summary
This summary is machine-generated.

This study introduces vmdMagazine, a VMD plugin that transforms computational simulations into engaging videos for education. It enhances understanding of molecular dynamics and atomic interactions for students and researchers.

Keywords:
Computational animationsComputerMicroscopic worldSoftware

More Related Videos

Visualization of Cortex Organization and Dynamics in Microorganisms, using Total Internal Reflection Fluorescence Microscopy
14:14

Visualization of Cortex Organization and Dynamics in Microorganisms, using Total Internal Reflection Fluorescence Microscopy

Published on: May 1, 2012

12.0K
Multimodal Hierarchical Imaging of Serial Sections for Finding Specific Cellular Targets within Large Volumes
11:19

Multimodal Hierarchical Imaging of Serial Sections for Finding Specific Cellular Targets within Large Volumes

Published on: March 20, 2018

10.9K

Related Experiment Videos

Last Updated: Feb 25, 2026

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy
11:26

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy

Published on: September 8, 2009

9.9K
Visualization of Cortex Organization and Dynamics in Microorganisms, using Total Internal Reflection Fluorescence Microscopy
14:14

Visualization of Cortex Organization and Dynamics in Microorganisms, using Total Internal Reflection Fluorescence Microscopy

Published on: May 1, 2012

12.0K
Multimodal Hierarchical Imaging of Serial Sections for Finding Specific Cellular Targets within Large Volumes
11:19

Multimodal Hierarchical Imaging of Serial Sections for Finding Specific Cellular Targets within Large Volumes

Published on: March 20, 2018

10.9K

Area of Science:

  • Computational science
  • Molecular visualization
  • Scientific education

Background:

  • Accurate visualization of microscopic worlds is crucial for scientific education.
  • Traditional methods may rely on approximations, potentially leading to misconceptions.
  • Engaging visual aids can improve student comprehension and interest in molecular concepts.

Purpose of the Study:

  • To introduce vmdMagazine, a novel plugin for Visual Molecular Dynamics (VMD).
  • To demonstrate the capability of vmdMagazine in converting computational simulations into high-impact video presentations.
  • To highlight the educational potential of the software for teaching atomic and molecular concepts.

Main Methods:

  • Development of a VMD plugin named vmdMagazine.
  • Utilizing computational simulation data as input.
  • Generating video presentations from simulation results.

Main Results:

  • vmdMagazine successfully converts complex computational simulations into visually appealing videos.
  • The generated videos are suitable for educational settings, including lectures and conferences.
  • The software facilitates a better understanding of atoms and molecules.

Conclusions:

  • vmdMagazine offers a powerful tool for enhancing scientific visualization in education.
  • The plugin bridges the gap between computational results and accessible learning experiences.
  • Accurate, simulation-based visualizations can foster greater interest and comprehension in molecular science.