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Related Concept Videos

Regional Terms01:12

Regional Terms

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Regional terms describe anatomy by dividing the body parts into different regions that contain structures involved in contributing similar functions. Using these terms helps increase the accurate description and identification of the particular region of interest or region affected by the disease.
Primarily, the human body has two major regions, the axial and appendicular regions. The axial region comprises regions from the head to the abdomen and makes up the central body axis. In contrast,...
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Region of Convergence01:17

Region of Convergence

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The z-transform is a powerful mathematical tool used in the analysis of discrete-time signals and systems. It is a crucial tool in the analysis of discrete-time systems, but its convergence is limited to specific values of the complex variable z. This range of values, known as the Region of Convergence (ROC), is fundamental in determining the behavior and stability of a system or signal. The ROC defines the region in the complex plane where the z-transform converges, which can take various...
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Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

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Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Anatomy of the Brain: Major Regions01:20

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The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
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Selected Data About Geographic Locations01:25

Selected Data About Geographic Locations

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Geographic Information Systems (GIS) rely on two core types of data: spatial data and attribute data.Spatial DataSpatial data defines the physical location of features within a coordinate system, typically expressed in terms of latitude and longitude. It provides precise positioning for elements like roads, rivers, or buildings.Attribute DataAttribute data complements spatial data by adding descriptive information about these features. For example, a road's spatial data includes its start and...
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Related Experiment Video

Updated: Feb 25, 2026

Cerebellar Regional Dissection for Molecular Analysis
08:51

Cerebellar Regional Dissection for Molecular Analysis

Published on: December 5, 2020

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Regional differences.

Zhou Yu1,2, Ting Chen2

  • 1Peking University-Tsinghua University-National Institute of Biological Sciences, Joint Graduate Program, School of Life Sciences, Tsinghua University, Beijing, China.

Elife
|August 10, 2017
PubMed
Summary
This summary is machine-generated.

Skin exhibits diverse hair follicle behaviors across its complex landscape. Understanding these regional differences is key to advancing dermatological research and treatments.

Keywords:
computational biologydevelopmental biologyhair folliclemousepattern formationskinstem cellssystems biologytissue regeneration

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Area of Science:

  • Dermatology and skin biology.
  • Cellular and molecular biology of the skin.

Background:

  • The skin's surface is not uniform.
  • Hair follicles display varied activities in different body areas.

Purpose of the Study:

  • To investigate the heterogeneity of hair follicle behavior.
  • To map distinct functional regions within the skin's landscape.

Main Methods:

  • Histological analysis of skin samples.
  • In vivo imaging of hair follicle dynamics.
  • Molecular profiling of regional skin characteristics.

Main Results:

  • Identified distinct zones of hair follicle activity.
  • Characterized unique cellular and molecular signatures for each region.
  • Demonstrated differential growth cycles and responses to stimuli.

Conclusions:

  • Skin regions possess unique hair follicle behaviors.
  • This regionality influences skin physiology and pathology.
  • Further research into these differences can reveal new therapeutic targets.