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Itolizumab in Psoriasis

Ankita Srivastava1

  • 1Department of Skin and VD, JNU Institute for Medical Sciences and Research Centre, Jaipur, Rajasthan, India.

Indian Journal of Dermatology
|August 11, 2017
PubMed

A number of biologics is being used for the treatment of psoriasis. Itolizumab is one such agent which has been approved in India. It is an anti-CD6 monoclonal antibody that acts by binding to scavenger receptor cysteine-rich (SRCR) distal domain 1 of CD6. Itolizumab has been found to be safe, with infusion reactions as the most common adverse effect. However, its advantages and disadvantages over other biologicals and immunosuppressants need to be established. Also, its utility in treating other immune-mediated disorders is being explored.

Keywords:
Anti-CD6 monoclonal antibodyitolizumabpsoriasistreatment

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