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Updated: Feb 24, 2026

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Published on: January 23, 2026
Whole-lung lavage complicated with pneumothorax: a case report
Hyun-Joo Ahn1, Mikyung Yang1, Jie Ae Kim1
1Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Pulmonary alveolar proteinosis treatment was complicated by hypoxemia during one lung ventilation. A right pneumothorax was identified and treated, allowing successful completion of the procedure.
Area of Science:
- Pulmonology
- Critical Care Medicine
Background:
- Pulmonary alveolar proteinosis (PAP) management often requires whole lung lavage (WLL).
- One lung ventilation (OLV) is critical for performing unilateral WLL but can be limited by patient factors.
Purpose of the Study:
- To describe a case of severe hypoxemia during OLV in a PAP patient undergoing WLL.
- To identify the cause of hypoxemia and enable completion of left lung lavage.
Main Methods:
- A patient with PAP underwent right lung lavage, followed by an attempted left lung lavage using OLV.
- Severe hypoxemia occurred during attempted left lung lavage, prompting investigation.
- Chest X-ray revealed right pneumothorax, which was treated with a chest tube.
Main Results:
- The patient experienced severe hypoxemia (SpO2 < 80%) during right OLV for left lung lavage.
- Bronchoscopic examination confirmed correct tube placement, and medical interventions were ineffective.
- Resolution of right pneumothorax allowed successful completion of left lung lavage without significant complications.
Conclusions:
- Pneumothorax is a critical complication that can arise during OLV for WLL in PAP patients.
- Prompt diagnosis and management of pneumothorax are essential for patient safety and procedural success.
- This case highlights the importance of vigilant monitoring and reassessment during complex respiratory procedures.
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